TY  - GEN
AU  - Grasso,D
AU  - Garcia,M N
AU  - Hamidi,T
AU  - Cano,C
AU  - Calvo,E
AU  - Lomberk,G
AU  - Urrutia,R
AU  - Iovanna,J L
TI  - Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence
SN  - 1476-5403
PY  - 2015///0608
KW  - Animals
KW  - Carcinoma, Pancreatic Ductal
KW  - pathology
KW  - Cell Line
KW  - Cell Transformation, Neoplastic
KW  - genetics
KW  - Cellular Senescence
KW  - Cyclin-Dependent Kinase Inhibitor p27
KW  - biosynthesis
KW  - DNA-Binding Proteins
KW  - Forkhead Box Protein O3
KW  - Forkhead Transcription Factors
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Mice
KW  - Mice, Knockout
KW  - Neoplasm Proteins
KW  - Pancreatic Neoplasms
KW  - Proto-Oncogene Proteins p21(ras)
KW  - RNA Interference
KW  - RNA, Small Interfering
KW  - S-Phase Kinase-Associated Proteins
KW  - Up-Regulation
KW  - beta-Galactosidase
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/cdd.2014.74
ER  -