Cho, Jeonghee <br/><br/>
Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.  [electronic resource] 

 -  Molecular cancer  Jun 2014 
 - 141 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-4598 
<br/><br/><label>Standard No.: </label>10.1186/1476-4598-13-141  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenocarcinoma--drug therapy<br/>Antibodies, Monoclonal, Humanized--therapeutic use<br/>Antineoplastic Agents--therapeutic use<br/>Cetuximab<br/>Colorectal Neoplasms--drug therapy<br/>Drug Resistance, Neoplasm--genetics<br/>ErbB Receptors--antagonists & inhibitors<br/>Gene Expression<br/>High-Throughput Nucleotide Sequencing<br/>Humans<br/>Mutation<br/>Protein Kinase Inhibitors--therapeutic use<br/>Protein Multimerization<br/>Protein Structure, Tertiary