Hoffman, Paul S <br/><br/>
Preclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pylori.  [electronic resource] 

 -  Antimicrobial agents and chemotherapy  Aug 2014 
 - 4703-12 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1098-6596 
<br/><br/><label>Standard No.: </label>10.1128/AAC.03112-14  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Bacterial Agents--blood<br/>Area Under Curve<br/>Benzamides--blood<br/>Biological Availability<br/>Cell Line<br/>Cell Survival--drug effects<br/>Dogs<br/>Drug Evaluation, Preclinical<br/>Half-Life<br/>Helicobacter Infections--blood<br/>Helicobacter pylori--drug effects<br/>Hepatocytes--cytology<br/>Humans<br/>Male<br/>Microbial Sensitivity Tests<br/>Microbiota--drug effects<br/>Microsomes, Liver--drug effects<br/>Pyruvate Synthase--metabolism<br/>Rats<br/>Thiamine Pyrophosphate--metabolism<br/>Thiazoles--blood