TY - GEN AU - Zhang,Liwei AU - Chen,Lee H AU - Wan,Hong AU - Yang,Rui AU - Wang,Zhaohui AU - Feng,Jie AU - Yang,Shaohua AU - Jones,Siân AU - Wang,Sizhen AU - Zhou,Weixin AU - Zhu,Huishan AU - Killela,Patrick J AU - Zhang,Junting AU - Wu,Zhen AU - Li,Guilin AU - Hao,Shuyu AU - Wang,Yu AU - Webb,Joseph B AU - Friedman,Henry S AU - Friedman,Allan H AU - McLendon,Roger E AU - He,Yiping AU - Reitman,Zachary J AU - Bigner,Darell D AU - Yan,Hai TI - Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas SN - 1546-1718 PY - 2014///0904 KW - Brain Stem Neoplasms KW - genetics KW - Cell Proliferation KW - Cells, Cultured KW - Checkpoint Kinase 2 KW - metabolism KW - DNA Copy Number Variations KW - DNA Methylation KW - Exome KW - Gene Expression Profiling KW - Glioma KW - High-Throughput Nucleotide Sequencing KW - Histones KW - Humans KW - Immunoblotting KW - Immunoenzyme Techniques KW - Immunoprecipitation KW - Mutation KW - Phosphoprotein Phosphatases KW - Prognosis KW - Protein Phosphatase 2C KW - Survival Rate KW - Tumor Stem Cell Assay KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ng.2995 ER -