TY  - GEN
AU  - Alkhouri,H
AU  - Rumzhum,N N
AU  - Rahman,M M
AU  - FitzPatrick,M
AU  - de Pedro,M
AU  - Oliver,B G
AU  - Bourke,J E
AU  - Ammit,A J
TI  - TLR2 activation causes tachyphylaxis to β2 -agonists in vitro and ex vivo: modelling bacterial exacerbation
SN  - 1398-9995
PY  - 2015///0402
KW  - Adrenergic beta-2 Receptor Agonists
KW  - pharmacology
KW  - Animals
KW  - Anti-Asthmatic Agents
KW  - Asthma
KW  - immunology
KW  - Bacterial Infections
KW  - complications
KW  - Bronchi
KW  - drug effects
KW  - Cyclooxygenase 2
KW  - biosynthesis
KW  - Dinoprostone
KW  - Dual Specificity Phosphatase 1
KW  - Enzyme-Linked Immunosorbent Assay
KW  - Humans
KW  - In Vitro Techniques
KW  - Mice
KW  - Myocytes, Smooth Muscle
KW  - Real-Time Polymerase Chain Reaction
KW  - Receptors, Adrenergic, beta-2
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Tachyphylaxis
KW  - Toll-Like Receptor 2
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/all.12449
ER  -