TY  - GEN
AU  - Goswami,S
AU  - Yee,S W
AU  - Stocker,S
AU  - Mosley,J D
AU  - Kubo,M
AU  - Castro,R
AU  - Mefford,J A
AU  - Wen,C
AU  - Liang,X
AU  - Witte,J
AU  - Brett,C
AU  - Maeda,S
AU  - Simpson,M D
AU  - Hedderson,M M
AU  - Davis,R L
AU  - Roden,D M
AU  - Giacomini,K M
AU  - Savic,R M
TI  - Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin
SN  - 1532-6535
PY  - 2014///1016
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Biomarkers
KW  - metabolism
KW  - Diabetes Mellitus, Type 2
KW  - blood
KW  - Female
KW  - Genome-Wide Association Study
KW  - Glycated Hemoglobin
KW  - Hepatocyte Nuclear Factor 4
KW  - genetics
KW  - Homozygote
KW  - Humans
KW  - Hypoglycemic Agents
KW  - administration & dosage
KW  - Male
KW  - Metformin
KW  - Middle Aged
KW  - Models, Biological
KW  - Multivariate Analysis
KW  - PPAR alpha
KW  - Pharmacogenetics
KW  - Phenotype
KW  - Polymorphism, Single Nucleotide
KW  - Retrospective Studies
KW  - Sp1 Transcription Factor
KW  - Transcription Factors
KW  - Treatment Outcome
KW  - United States
KW  - Young Adult
N1  - Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1038/clpt.2014.109
ER  -