Goswami, S <br/><br/>
Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin.  [electronic resource] 

 -  Clinical pharmacology and therapeutics  Sep 2014 
 - 370-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1532-6535 
<br/><br/><label>Standard No.: </label>10.1038/clpt.2014.109  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Biomarkers--metabolism<br/>Diabetes Mellitus, Type 2--blood<br/>Female<br/>Genome-Wide Association Study<br/>Glycated Hemoglobin--metabolism<br/>Hepatocyte Nuclear Factor 4--genetics<br/>Homozygote<br/>Humans<br/>Hypoglycemic Agents--administration & dosage<br/>Male<br/>Metformin--administration & dosage<br/>Middle Aged<br/>Models, Biological<br/>Multivariate Analysis<br/>PPAR alpha--genetics<br/>Pharmacogenetics<br/>Phenotype<br/>Polymorphism, Single Nucleotide<br/>Retrospective Studies<br/>Sp1 Transcription Factor--genetics<br/>Transcription Factors--genetics<br/>Treatment Outcome<br/>United States<br/>Young Adult