The epigenetic bivalency of core pancreatic β-cell transcription factor genes within mouse pluripotent embryonic stem cells is not affected by knockdown of the polycomb repressive complex 2, SUZ12. [electronic resource]
- PloS one 2014
- e97820 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0097820 doi
Animals Cell Line Embryonic Stem Cells--metabolism Epigenesis, Genetic Gene Expression Profiling Gene Expression Regulation Gene Knockdown Techniques Histones--metabolism Homeobox Protein Nkx-2.2 Insulin-Secreting Cells--metabolism Jumonji Domain-Containing Histone Demethylases--genetics Mice Pluripotent Stem Cells--metabolism Polycomb Repressive Complex 2--genetics Protein Binding RNA, Small Interfering--genetics Reproducibility of Results Transcription Factors--genetics