TY - GEN AU - Carvalho,Sílvia AU - Vítor,Alexandra C AU - Sridhara,Sreerama C AU - Martins,Filipa B AU - Raposo,Ana C AU - Desterro,Joana M P AU - Ferreira,João AU - de Almeida,Sérgio F TI - SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint SN - 2050-084X PY - 2015///1123 KW - Ataxia Telangiectasia Mutated Proteins KW - metabolism KW - Carcinoma, Renal Cell KW - Cell Cycle Checkpoints KW - genetics KW - Cell Line, Tumor KW - Cell Survival KW - DNA Breaks, Double-Stranded KW - DNA Repair KW - Histone-Lysine N-Methyltransferase KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Kidney Neoplasms KW - Mutation KW - Protein Binding KW - Rad51 Recombinase KW - Recombination, Genetic KW - Recombinational DNA Repair KW - Replication Protein A KW - Signal Transduction KW - Tumor Suppressor Protein p53 KW - Tumor Suppressor p53-Binding Protein 1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.7554/eLife.02482 ER -