Nave, Alexander H

Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Jul 2014 - 1446-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4636

10.1161/ATVBAHA.114.303534 doi


Adult
Aged, 80 and over
Animals
Antihypertensive Agents--pharmacology
Case-Control Studies
Cell Hypoxia
Cells, Cultured
Collagen--metabolism
Disease Models, Animal
Elastin--metabolism
Enzyme Inhibitors--pharmacology
Familial Primary Pulmonary Hypertension
Female
Fibroblasts--enzymology
Gene Expression Regulation, Enzymologic
Humans
Hypertension, Pulmonary--drug therapy
Hypertrophy, Right Ventricular--enzymology
Hypoxia--complications
Isoenzymes
Male
Mice
Middle Aged
Monocrotaline
Muscle, Smooth, Vascular--enzymology
Myocytes, Smooth Muscle--enzymology
Protein-Lysine 6-Oxidase--antagonists & inhibitors
Pulmonary Artery--drug effects
RNA, Messenger--metabolism
Rats
Ventricular Dysfunction, Right--enzymology
Young Adult