Kern, Georg <br/><br/>
Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling.  [electronic resource] 

 -  PloS one  2014 
 - e96377 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0096377  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Blotting, Western<br/>Calcineurin Inhibitors--pharmacology<br/>Cell Line<br/>Collagen Type V--genetics<br/>Fibroblasts--drug effects<br/>Fibrosis--genetics<br/>Gene Expression--drug effects<br/>Gene Expression Profiling<br/>Humans<br/>Hydrogen Peroxide--metabolism<br/>Kidney--metabolism<br/>NADPH Oxidase 4<br/>NADPH Oxidases--genetics<br/>Oligonucleotide Array Sequence Analysis<br/>Phosphorylation--drug effects<br/>Procollagen--genetics<br/>RNA Interference<br/>Receptors, Transforming Growth Factor beta--genetics<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Signal Transduction--drug effects<br/>Smad2 Protein--metabolism<br/>Tacrolimus--pharmacology