Gao, Ling

IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma. [electronic resource] - Oncotarget May 2014 - 2562-74 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1949-2553

10.18632/oncotarget.1812 doi


Animals
Apoptosis
Blotting, Western
Carcinoma, Squamous Cell--genetics
Cell Cycle
Cell Differentiation
Cell Proliferation
Female
Gene Expression Regulation, Neoplastic
Humans
Immunoenzyme Techniques
Insulin Receptor Substrate Proteins--antagonists & inhibitors
Male
Mice
Mice, Inbred BALB C
Mice, Nude
MicroRNAs--genetics
Middle Aged
Mitogen-Activated Protein Kinases--genetics
Mouth Neoplasms--genetics
Phosphatidylinositol 3-Kinases--genetics
Phosphorylation
Proto-Oncogene Proteins c-akt--genetics
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Receptor, IGF Type 1--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Tumor Cells, Cultured
Xenograft Model Antitumor Assays