TY - GEN AU - Krug,A K AU - Gutbier,S AU - Zhao,L AU - Pöltl,D AU - Kullmann,C AU - Ivanova,V AU - Förster,S AU - Jagtap,S AU - Meiser,J AU - Leparc,G AU - Schildknecht,S AU - Adam,M AU - Hiller,K AU - Farhan,H AU - Brunner,T AU - Hartung,T AU - Sachinidis,A AU - Leist,M TI - Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+) SN - 2041-4889 PY - 2014///1021 KW - 1-Methyl-4-phenylpyridinium KW - toxicity KW - Activating Transcription Factor 4 KW - genetics KW - Adaptation, Physiological KW - Adenosine Triphosphate KW - metabolism KW - Cell Line KW - Computational Biology KW - Dopaminergic Neurons KW - drug effects KW - Energy Metabolism KW - Gene Expression Profiling KW - methods KW - Gene Expression Regulation KW - Glucose KW - Glutathione KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Mass Spectrometry KW - Metabolomics KW - Mitochondria KW - Neural Stem Cells KW - Neurotoxicity Syndromes KW - etiology KW - Oligonucleotide Array Sequence Analysis KW - Oxidative Stress KW - Phosphocreatine KW - RNA Interference KW - Time Factors KW - Transcription, Genetic KW - Transfection N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1038/cddis.2014.166 ER -