TY  - GEN
AU  - Fan,Jing
AU  - Ye,Jiangbin
AU  - Kamphorst,Jurre J
AU  - Shlomi,Tomer
AU  - Thompson,Craig B
AU  - Rabinowitz,Joshua D
TI  - Quantitative flux analysis reveals folate-dependent NADPH production
SN  - 1476-4687
PY  - 2014///0715
KW  - Animals
KW  - Carbon
KW  - metabolism
KW  - Cell Line
KW  - Cell Line, Tumor
KW  - Cytosol
KW  - enzymology
KW  - Folic Acid
KW  - Glutathione
KW  - Glycine
KW  - HEK293 Cells
KW  - Humans
KW  - Isoenzymes
KW  - deficiency
KW  - Leucovorin
KW  - analogs & derivatives
KW  - Methylenetetrahydrofolate Dehydrogenase (NADP)
KW  - Mice
KW  - Mitochondria
KW  - NADP
KW  - biosynthesis
KW  - Oxidation-Reduction
KW  - Oxidative Stress
KW  - Pentose Phosphate Pathway
KW  - Serine
KW  - Tetrahydrofolates
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature13236
ER  -