TY  - GEN
AU  - Lee,Jung-Hoon
AU  - Kang,Eunji
AU  - Lee,Jungmin
AU  - Kim,Jungmin
AU  - Lee,Kyoung Hu
AU  - Han,Jieun
AU  - Kang,Hye Yoon
AU  - Ahn,Soshin
AU  - Oh,Youngmi
AU  - Shin,Dongkyu
AU  - Hur,Kyeyeon
AU  - Chae,Su Young
AU  - Song,Paul H
AU  - Kim,Yong-In
AU  - Park,Jae Chan
AU  - Lee,Jae Il
TI  - Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor
SN  - 2041-1723
PY  - 2015///0804
KW  - Amino Acid Sequence
KW  - Animals
KW  - Apoptosis
KW  - genetics
KW  - Cell Cycle Checkpoints
KW  - Cell Cycle Proteins
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Cell Survival
KW  - Crystallography, X-Ray
KW  - Female
KW  - HCT116 Cells
KW  - Humans
KW  - Leucine Zippers
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Molecular Dynamics Simulation
KW  - Multiprotein Complexes
KW  - ultrastructure
KW  - Neoplasm Transplantation
KW  - Neoplasms
KW  - drug therapy
KW  - Nuclear Proteins
KW  - antagonists & inhibitors
KW  - Protein Engineering
KW  - Protein Structure, Tertiary
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-mdm2
KW  - Recombinant Proteins
KW  - pharmacology
KW  - Sequence Alignment
KW  - Transplantation, Heterologous
KW  - Tumor Suppressor Protein p53
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/ncomms4814
ER  -