Lee, Jung-Hoon <br/><br/>
Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.  [electronic resource] 

 -  Nature communications  May 2014 
 - 3814 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-1723 
<br/><br/><label>Standard No.: </label>10.1038/ncomms4814  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Animals<br/>Apoptosis--genetics<br/>Cell Cycle Checkpoints--genetics<br/>Cell Cycle Proteins<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Crystallography, X-Ray<br/>Female<br/>HCT116 Cells<br/>Humans<br/>Leucine Zippers--genetics<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Molecular Dynamics Simulation<br/>Multiprotein Complexes--ultrastructure<br/>Neoplasm Transplantation<br/>Neoplasms--drug therapy<br/>Nuclear Proteins--antagonists & inhibitors<br/>Protein Engineering<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Recombinant Proteins--pharmacology<br/>Sequence Alignment<br/>Transplantation, Heterologous<br/>Tumor Suppressor Protein p53--chemistry