TY - GEN AU - Arslanbekova,S M AU - Sychev,D A AU - Kazakov,R E AU - Smirnov,V V AU - Kuznetsova,E V AU - Golukhova,E Z TI - [Relationship between warfarin dosing and activity of CYP2C9 assessed by the content of losartan and its metabolite E-3174 in the urine of patients with mechanical prosthetic heart valves] SN - 0022-9040 PY - 2014///0723 KW - Adult KW - Anticoagulants KW - pharmacokinetics KW - Aryl Hydrocarbon Hydroxylases KW - genetics KW - Biotransformation KW - Cardiovascular Agents KW - Cytochrome P-450 CYP2C9 KW - Dose-Response Relationship, Drug KW - Drug Monitoring KW - methods KW - Female KW - Genotype KW - Heart Valve Diseases KW - drug therapy KW - Heart Valve Prosthesis Implantation KW - Humans KW - Imidazoles KW - Losartan KW - Male KW - Middle Aged KW - Pharmacogenetics KW - Polymorphism, Genetic KW - Postoperative Period KW - Tetrazoles KW - Warfarin N1 - Publication Type: Journal Article ER -