Akuta, Norio <br/><br/>
Evolution of simeprevir-resistant variants over time by ultra-deep sequencing in HCV genotype 1b.  [electronic resource] 

 -  Journal of medical virology  Aug 2014 
 - 1314-22 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1096-9071 
<br/><br/><label>Standard No.: </label>10.1002/jmv.23966  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Antiviral Agents--pharmacology<br/>Drug Resistance, Viral<br/>Female<br/>Genotype<br/>Hepacivirus--drug effects<br/>Hepatitis C--drug therapy<br/>Heterocyclic Compounds, 3-Ring--pharmacology<br/>High-Throughput Nucleotide Sequencing<br/>Humans<br/>Interferon-alpha--therapeutic use<br/>Japan<br/>Male<br/>Middle Aged<br/>RNA, Viral--genetics<br/>Ribavirin--therapeutic use<br/>Simeprevir<br/>Sulfonamides--pharmacology<br/>Treatment Failure<br/>Viral Load<br/>Young Adult