Chen, Xiaoyun
The complex interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells. [electronic resource]
- PloS one 2014
- e96365 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1932-6203
Standard No.: 10.1371/journal.pone.0096365 doi
Subjects--Topical Terms: Benzamides--pharmacology Blotting, Western Butadienes--pharmacology Calcium-Binding Proteins--genetics Cell Line Dioxoles--pharmacology Enzyme Inhibitors--pharmacology Epithelial Cells--drug effects Epithelial-Mesenchymal Transition--drug effects Gene Expression--drug effects Humans Intercellular Signaling Peptides and Proteins--genetics Jagged-1 Protein MAP Kinase Signaling System--drug effects Membrane Proteins--genetics Mitogen-Activated Protein Kinase 1--antagonists & inhibitors Mitogen-Activated Protein Kinase 3--antagonists & inhibitors Multiprotein Complexes--metabolism Nitriles--pharmacology Receptor, Notch3 Receptors, Notch--genetics Retinal Pigment Epithelium--cytology Reverse Transcriptase Polymerase Chain Reaction Serrate-Jagged Proteins Signal Transduction--drug effects Smad Proteins--metabolism Smad2 Protein--metabolism Smad3 Protein--metabolism Transforming Growth Factor beta2--pharmacology