Chen, Xiaoyun

The complex interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells. [electronic resource] - PloS one 2014 - e96365 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0096365 doi


Benzamides--pharmacology
Blotting, Western
Butadienes--pharmacology
Calcium-Binding Proteins--genetics
Cell Line
Dioxoles--pharmacology
Enzyme Inhibitors--pharmacology
Epithelial Cells--drug effects
Epithelial-Mesenchymal Transition--drug effects
Gene Expression--drug effects
Humans
Intercellular Signaling Peptides and Proteins--genetics
Jagged-1 Protein
MAP Kinase Signaling System--drug effects
Membrane Proteins--genetics
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3--antagonists & inhibitors
Multiprotein Complexes--metabolism
Nitriles--pharmacology
Receptor, Notch3
Receptors, Notch--genetics
Retinal Pigment Epithelium--cytology
Reverse Transcriptase Polymerase Chain Reaction
Serrate-Jagged Proteins
Signal Transduction--drug effects
Smad Proteins--metabolism
Smad2 Protein--metabolism
Smad3 Protein--metabolism
Transforming Growth Factor beta2--pharmacology