Induction of p21CIP1 protein and cell cycle arrest after inhibition of Aurora B kinase is attributed to aneuploidy and reactive oxygen species. [electronic resource]
- The Journal of biological chemistry Jun 2014
- 16072-84 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M114.555060 doi
Aneuploidy Aurora Kinase B--drug effects Cell Cycle Cell Line Cyclin-Dependent Kinase Inhibitor p21--biosynthesis Flow Cytometry Humans In Situ Hybridization, Fluorescence Protein Kinase Inhibitors--pharmacology Reactive Oxygen Species--metabolism Signal Transduction p38 Mitogen-Activated Protein Kinases--metabolism