p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine. [electronic resource]
- Journal of experimental & clinical cancer research : CR Apr 2014
- 36 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1756-9966
10.1186/1756-9966-33-36 doi
Adenocarcinoma Adenocarcinoma of Lung Antineoplastic Agents--pharmacology Apoptosis Berberine--pharmacology Cell Line, Tumor Cell Proliferation Cyclin-Dependent Kinase Inhibitor p21--genetics Forkhead Box Protein O3 Forkhead Transcription Factors--genetics G1 Phase Cell Cycle Checkpoints--drug effects Gene Expression Gene Expression Regulation, Neoplastic--drug effects Humans Lung Neoplasms MAP Kinase Signaling System Mitogen-Activated Protein Kinase 14--physiology Phosphorylation Protein Processing, Post-Translational Transcriptional Activation Tumor Suppressor Protein p53--genetics