TY  - GEN
AU  - MacLean,David B
AU  - Matsui,Hisanori
AU  - Suri,Ajit
AU  - Neuwirth,Rachel
AU  - Colombel,Marc
TI  - Sustained exposure to the investigational Kisspeptin analog, TAK-448, down-regulates testosterone into the castration range in healthy males and in patients with prostate cancer: results from two phase 1 studies
SN  - 1945-7197
PY  - 2014///1027
KW  - Adult
KW  - Aged
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - drug effects
KW  - Drug Administration Schedule
KW  - Drugs, Investigational
KW  - administration & dosage
KW  - Health
KW  - Humans
KW  - Kisspeptins
KW  - Luteinizing Hormone
KW  - blood
KW  - Male
KW  - Middle Aged
KW  - Orchiectomy
KW  - Placebos
KW  - Prostatic Neoplasms
KW  - Testosterone
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1210/jc.2013-4236
ER  -