Li, Baomin <br/><br/>
Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells.  [electronic resource] 

 -  Aging cell  04 2014 
 - 367-78 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1474-9726 
<br/><br/><label>Standard No.: </label>10.1111/acel.12181  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antioxidants--pharmacology<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Respiration--drug effects<br/>Cellular Senescence--drug effects<br/>DNA Damage<br/>Down-Regulation--drug effects<br/>Energy Metabolism--drug effects<br/>Exodeoxyribonucleases--genetics<br/>Gene Knockdown Techniques<br/>Glutathione--metabolism<br/>Homeostasis--drug effects<br/>Humans<br/>Hypoxia-Inducible Factor 1, alpha Subunit--metabolism<br/>Macromolecular Substances--metabolism<br/>Mice<br/>Mitochondria--drug effects<br/>Neoplasms--metabolism<br/>Niacinamide--metabolism<br/>Oxidation-Reduction--drug effects<br/>Oxidative Stress--drug effects<br/>Reactive Oxygen Species--metabolism<br/>RecQ Helicases--genetics<br/>Werner Syndrome--genetics<br/>Werner Syndrome Helicase