Pepinsky, R Blake

Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2014 - 110-23 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1521-0103

10.1124/jpet.113.211771 doi


Animals
Antibodies, Monoclonal--metabolism
Cell Differentiation--immunology
Female
Humans
Immunoglobulin Fab Fragments--metabolism
Membrane Proteins--metabolism
Molecular Structure
Multiple Sclerosis--drug therapy
Nerve Tissue Proteins--metabolism
Oligodendroglia--immunology
Protein Binding
Protein Structure, Quaternary
Rats