TY  - GEN
AU  - Schoumacher,Marie
AU  - Hurov,Kristen E
AU  - Lehár,Joseph
AU  - Yan-Neale,Yan
AU  - Mishina,Yuji
AU  - Sonkin,Dmitriy
AU  - Korn,Joshua M
AU  - Flemming,Daisy
AU  - Jones,Michael D
AU  - Antonakos,Brandon
AU  - Cooke,Vesselina G
AU  - Steiger,Janine
AU  - Ledell,Jebediah
AU  - Stump,Mark D
AU  - Sellers,William R
AU  - Danial,Nika N
AU  - Shao,Wenlin
TI  - Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling
SN  - 1538-7445
PY  - 2014///0808
KW  - Acetamides
KW  - administration & dosage
KW  - Aminopyridines
KW  - Aniline Compounds
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Drug Synergism
KW  - Erlotinib Hydrochloride
KW  - Feedback, Physiological
KW  - Female
KW  - Humans
KW  - MAP Kinase Kinase Kinases
KW  - antagonists & inhibitors
KW  - Mice
KW  - Mice, Nude
KW  - Morpholines
KW  - Mutation
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins
KW  - genetics
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Pyrimidinones
KW  - Quinazolines
KW  - Receptor, Fibroblast Growth Factor, Type 2
KW  - Signal Transduction
KW  - Sulfonamides
KW  - Tankyrases
KW  - Thiazoles
KW  - Xenograft Model Antitumor Assays
KW  - ras Proteins
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1158/0008-5472.CAN-14-0138-T
ER  -