TY  - GEN
AU  - Liu,Meilian
AU  - Bai,Juli
AU  - He,Sijia
AU  - Villarreal,Ricardo
AU  - Hu,Derong
AU  - Zhang,Chuntao
AU  - Yang,Xin
AU  - Liang,Huiyun
AU  - Slaga,Thomas J
AU  - Yu,Yonghao
AU  - Zhou,Zhiguang
AU  - Blenis,John
AU  - Scherer,Philipp E
AU  - Dong,Lily Q
AU  - Liu,Feng
TI  - Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1
SN  - 1932-7420
PY  - 2015///0615
KW  - Adaptor Proteins, Signal Transducing
KW  - metabolism
KW  - Adipose Tissue, Brown
KW  - Adipose Tissue, White
KW  - Animals
KW  - Antibiotics, Antineoplastic
KW  - pharmacology
KW  - Cells, Cultured
KW  - Cold Temperature
KW  - Cold-Shock Response
KW  - Diabetes Mellitus
KW  - Energy Metabolism
KW  - physiology
KW  - Feedback, Physiological
KW  - GRB10 Adaptor Protein
KW  - biosynthesis
KW  - Insulin Resistance
KW  - Lipolysis
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice
KW  - Mice, Knockout
KW  - Multiprotein Complexes
KW  - antagonists & inhibitors
KW  - Obesity
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphorylation
KW  - Protein Binding
KW  - Proto-Oncogene Proteins c-akt
KW  - Receptor, Insulin
KW  - Regulatory-Associated Protein of mTOR
KW  - Signal Transduction
KW  - Sirolimus
KW  - TOR Serine-Threonine Kinases
KW  - Thermogenesis
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.cmet.2014.03.018
ER  -