TY - GEN AU - Tong,Hua Hua AU - Lambert,Garrett AU - Li,Yong Xing AU - Thurman,Joshua M AU - Stahl,Gregory L AU - Douthitt,Kelsey AU - Clancy,Caitlin AU - He,Yujuan AU - Bowman,Andrew S TI - Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice SN - 1932-6203 PY - 2015///0601 KW - Acute Disease KW - Animals KW - Coinfection KW - Complement Activation KW - Complement C1q KW - deficiency KW - Complement C3a KW - genetics KW - Complement C5a KW - Complement Factor B KW - Eustachian Tube KW - immunology KW - Female KW - Gene Deletion KW - Gene Expression KW - Immunity, Innate KW - Influenza A Virus, H1N1 Subtype KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Orthomyxoviridae Infections KW - Otitis Media KW - Pneumococcal Infections KW - Receptor, Anaphylatoxin C5a KW - Severity of Illness Index KW - Streptococcus pneumoniae N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1371/journal.pone.0095160 ER -