TY  - GEN
AU  - Schiebel,Johannes
AU  - Chang,Andrew
AU  - Shah,Sonam
AU  - Lu,Yang
AU  - Liu,Li
AU  - Pan,Pan
AU  - Hirschbeck,Maria W
AU  - Tareilus,Mona
AU  - Eltschkner,Sandra
AU  - Yu,Weixuan
AU  - Cummings,Jason E
AU  - Knudson,Susan E
AU  - Bommineni,Gopal R
AU  - Walker,Stephen G
AU  - Slayden,Richard A
AU  - Sotriffer,Christoph A
AU  - Tonge,Peter J
AU  - Kisker,Caroline
TI  - Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor
SN  - 1083-351X
PY  - 2014///1007
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - chemistry
KW  - Base Sequence
KW  - Crystallography, X-Ray
KW  - DNA Primers
KW  - Drug Design
KW  - Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)
KW  - antagonists & inhibitors
KW  - Enzyme Inhibitors
KW  - Female
KW  - Mice
KW  - Mice, Inbred ICR
KW  - Microbial Sensitivity Tests
KW  - Molecular Structure
KW  - Polymerase Chain Reaction
KW  - Pyridones
KW  - Staphylococcus aureus
KW  - drug effects
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M113.532804
ER  -