Yellapu, Nandakumar <br/><br/>
Mutations in exons 10 and 11 of human glucokinase result in conformational variations in the active site of the structure contributing to poor substrate binding - explains hyperglycemia in type 2 diabetic patients.  [electronic resource] 

 -  Journal of biomolecular structure & dynamics  2015 
 - 820-33 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-0254 
<br/><br/><label>Standard No.: </label>10.1080/07391102.2014.913989  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Catalytic Domain<br/>DNA Mutational Analysis<br/>Diabetes Mellitus, Type 2--enzymology<br/>Exons<br/>Genetic Association Studies<br/>Glucokinase--chemistry<br/>Glucose--chemistry<br/>Humans<br/>Hyperglycemia--enzymology<br/>Molecular Docking Simulation<br/>Mutation, Missense<br/>Protein Binding