TY - GEN AU - Morran,Douglas C AU - Wu,Jianmin AU - Jamieson,Nigel B AU - Mrowinska,Agata AU - Kalna,Gabriela AU - Karim,Saadia A AU - Au,Amy Y M AU - Scarlett,Christopher J AU - Chang,David K AU - Pajak,Malgorzata Z AU - Oien,Karin A AU - McKay,Colin J AU - Carter,C Ross AU - Gillen,Gerry AU - Champion,Sue AU - Pimlott,Sally L AU - Anderson,Kurt I AU - Evans,T R Jeffry AU - Grimmond,Sean M AU - Biankin,Andrew V AU - Sansom,Owen J AU - Morton,Jennifer P TI - Targeting mTOR dependency in pancreatic cancer SN - 1468-3288 PY - 2014///0930 KW - Animals KW - Antineoplastic Agents KW - therapeutic use KW - Biomarkers, Tumor KW - antagonists & inhibitors KW - Carcinoma, Pancreatic Ductal KW - diagnostic imaging KW - Cell Line, Tumor KW - Drug Administration Schedule KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Injections, Intraperitoneal KW - Mice KW - Mice, Mutant Strains KW - Mutation KW - PTEN Phosphohydrolase KW - deficiency KW - Pancreatic Neoplasms KW - Positron-Emission Tomography KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins p21(ras) KW - Sirolimus KW - TOR Serine-Threonine Kinases KW - Treatment Outcome KW - Tumor Suppressor Protein p53 N1 - Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1136/gutjnl-2013-306202 ER -