Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice. [electronic resource]
- PloS one 2014
- e92684 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0092684 doi
Adipose Tissue--immunology Animals Cell Proliferation--drug effects Dietary Fats--adverse effects Disease Models, Animal Female Immunosuppressive Agents--pharmacology Insulin Resistance--immunology Liver--immunology Male Mechanistic Target of Rapamycin Complex 1 Mechanistic Target of Rapamycin Complex 2 Mice Multiprotein Complexes--immunology Myeloid Cells--immunology Obesity--chemically induced Signal Transduction--drug effects Sirolimus--pharmacology T-Lymphocytes, Regulatory--immunology TOR Serine-Threonine Kinases--immunology