Nomura, Johji <br/><br/>
Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice.  [electronic resource] 

 -  Scientific reports  Apr 2014 
 - 4554 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep04554  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aorta--cytology<br/>Apolipoproteins E--genetics<br/>Atherosclerosis--drug therapy<br/>Body Weight<br/>Cholesterol--blood<br/>Cytokines--metabolism<br/>Disease Models, Animal<br/>Endothelial Cells--metabolism<br/>Febuxostat<br/>Gout Suppressants--pharmacology<br/>Inflammation--drug therapy<br/>L-Lactate Dehydrogenase--metabolism<br/>Macrophages--metabolism<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Oxidative Stress--drug effects<br/>Plaque, Atherosclerotic--pathology<br/>Reactive Oxygen Species--metabolism<br/>Thiazoles--pharmacology<br/>Xanthine Oxidase--antagonists & inhibitors