TY - GEN AU - Saleem,Muhammad AU - Yu,Seon-Mi AU - Rafiq,Muhammad AU - Kim,Song-Ja AU - Seo,Sung-Yum AU - Lee,Ki Hwan TI - Synthesis, crystal structure, anti-inflammatory and anti-hyperglycemic activities of novel 3,4-disubstituted 1,2,4-triazol-5(4H)-one derivatives SN - 1875-6638 PY - 2015///0619 KW - Acarbose KW - pharmacology KW - Animals KW - Anti-Inflammatory Agents KW - chemical synthesis KW - Cartilage, Articular KW - cytology KW - Cattle KW - Cells, Cultured KW - Chondrocytes KW - Collagen Type II KW - genetics KW - Crystallography, X-Ray KW - Cyclization KW - Cyclooxygenase 2 KW - Dose-Response Relationship, Drug KW - Enzyme Assays KW - Gene Expression KW - Hydrazines KW - chemistry KW - Hypoglycemic Agents KW - Isocyanates KW - Molecular Structure KW - Rabbits KW - Swine KW - Triazoles KW - alpha-Amylases KW - antagonists & inhibitors KW - alpha-Glucosidases KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2174/1573406410666140327142912 ER -