TY  - GEN
AU  - Wenglowsky,Steve
AU  - Ren,Li
AU  - Grina,Jonas
AU  - Hansen,Joshua D
AU  - Laird,Ellen R
AU  - Moreno,David
AU  - Dinkel,Victoria
AU  - Gloor,Susan L
AU  - Hastings,Gregg
AU  - Rana,Sumeet
AU  - Rasor,Kevin
AU  - Sturgis,Hillary L
AU  - Voegtli,Walter C
AU  - Vigers,Guy
AU  - Willis,Brandon
AU  - Mathieu,Simon
AU  - Rudolph,Joachim
TI  - Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase
SN  - 1464-3405
PY  - 2014///1020
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Enzyme Activation
KW  - drug effects
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Molecular Structure
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins B-raf
KW  - antagonists & inhibitors
KW  - Quinazolines
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2014.03.007
ER  -