Wenglowsky, Steve <br/><br/>
Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Apr 2014 
 - 1923-7 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2014.03.007  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Crystallography, X-Ray<br/>Drug Design<br/>Enzyme Activation--drug effects<br/>Humans<br/>Inhibitory Concentration 50<br/>Molecular Structure<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Quinazolines--chemical synthesis<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays