TY - GEN AU - Birsoy,Kıvanç AU - Possemato,Richard AU - Lorbeer,Franziska K AU - Bayraktar,Erol C AU - Thiru,Prathapan AU - Yucel,Burcu AU - Wang,Tim AU - Chen,Walter W AU - Clish,Clary B AU - Sabatini,David M TI - Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides SN - 1476-4687 PY - 2014///0422 KW - Adenosine Triphosphate KW - metabolism KW - Animals KW - Biguanides KW - pharmacology KW - Cell Culture Techniques KW - instrumentation KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Culture Media KW - chemistry KW - DNA, Mitochondrial KW - genetics KW - Electron Transport Complex I KW - deficiency KW - Glucose KW - Humans KW - Hypoglycemic Agents KW - Male KW - Mice KW - Mitochondria KW - Molecular Typing KW - Mutation KW - Neoplasm Transplantation KW - Neoplasms KW - drug therapy KW - Oxidative Phosphorylation KW - Phenformin KW - RNA Interference KW - Saccharomyces cerevisiae Proteins KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nature13110 ER -