Uhmann, Anja

DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice. [electronic resource] - The Journal of investigative dermatology Oct 2014 - 2620-2629 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1523-1747

10.1038/jid.2014.157 doi


9,10-Dimethyl-1,2-benzanthracene--adverse effects
Alleles
Animals
CD4-Positive T-Lymphocytes--pathology
Carcinogenesis--chemically induced
Carcinogens--pharmacology
Carcinoma, Basal Cell--chemically induced
Disease Models, Animal
Epidermis--pathology
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Mutation--genetics
Patched Receptors
Patched-1 Receptor
Proto-Oncogene Proteins p21(ras)--genetics
Receptors, Cell Surface--deficiency
Signal Transduction--physiology
Skin Neoplasms--chemically induced
Stem Cells--pathology
Tetradecanoylphorbol Acetate--adverse effects