Fan, Xing-Xing <br/><br/>
Celastrol induces apoptosis in gefitinib-resistant non-small cell lung cancer cells via caspases-dependent pathways and Hsp90 client protein degradation.  [electronic resource] 

 -  Molecules (Basel, Switzerland)  Mar 2014 
 - 3508-22 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1420-3049 
<br/><br/><label>Standard No.: </label>10.3390/molecules19033508  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Carcinoma, Non-Small-Cell Lung--metabolism<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm<br/>Gefitinib<br/>HSP90 Heat-Shock Proteins--metabolism<br/>Humans<br/>Inhibitory Concentration 50<br/>Lung Neoplasms--metabolism<br/>Mitochondria--drug effects<br/>Pentacyclic Triterpenes<br/>Protein Kinase Inhibitors--pharmacology<br/>Proteolysis--drug effects<br/>Quinazolines--pharmacology<br/>Signal Transduction--drug effects<br/>Triterpenes--pharmacology