TY - GEN AU - Warboys,Christina M AU - de Luca,Amalia AU - Amini,Narges AU - Luong,Le AU - Duckles,Hayley AU - Hsiao,Sarah AU - White,Alex AU - Biswas,Shukti AU - Khamis,Ramzi AU - Chong,Chuh K AU - Cheung,Wai-Mun AU - Sherwin,Spencer J AU - Bennett,Martin R AU - Gil,Jesus AU - Mason,Justin C AU - Haskard,Dorian O AU - Evans,Paul C TI - Disturbed flow promotes endothelial senescence via a p53-dependent pathway SN - 1524-4636 PY - 2014///0620 KW - Animals KW - Aortic Diseases KW - genetics KW - Atherosclerosis KW - Bioreactors KW - Cell Movement KW - Cells, Cultured KW - Cellular Senescence KW - drug effects KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Diet, High-Fat KW - Disease Models, Animal KW - Endothelial Cells KW - Enzyme Activation KW - Enzyme Activators KW - pharmacology KW - Human Umbilical Vein Endothelial Cells KW - metabolism KW - Humans KW - Mechanotransduction, Cellular KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - RNA Interference KW - Receptors, LDL KW - deficiency KW - Regional Blood Flow KW - Sirtuin 1 KW - Stress, Mechanical KW - Swine KW - Time Factors KW - Transfection KW - Tumor Suppressor Protein p53 KW - Wound Healing N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1161/ATVBAHA.114.303415 ER -