Warboys, Christina M

Disturbed flow promotes endothelial senescence via a p53-dependent pathway. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology May 2014 - 985-95 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4636

10.1161/ATVBAHA.114.303415 doi


Animals
Aortic Diseases--genetics
Atherosclerosis--genetics
Bioreactors
Cell Movement
Cells, Cultured
Cellular Senescence--drug effects
Cyclin-Dependent Kinase Inhibitor p21--genetics
Diet, High-Fat
Disease Models, Animal
Endothelial Cells--drug effects
Enzyme Activation
Enzyme Activators--pharmacology
Human Umbilical Vein Endothelial Cells--metabolism
Humans
Mechanotransduction, Cellular--drug effects
Mice
Mice, Inbred C57BL
Mice, Knockout
RNA Interference
Receptors, LDL--deficiency
Regional Blood Flow
Sirtuin 1--metabolism
Stress, Mechanical
Swine
Time Factors
Transfection
Tumor Suppressor Protein p53--genetics
Wound Healing