Sun, Yu'e

Intrathecal injection of JWH015 attenuates remifentanil-induced postoperative hyperalgesia by inhibiting activation of spinal glia in a rat model. [electronic resource] - Anesthesia and analgesia Apr 2014 - 841-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1526-7598

10.1213/ANE.0000000000000146 doi


Anesthetics, Local--antagonists & inhibitors
Animals
Astrocytes--drug effects
Behavior, Animal--drug effects
Blotting, Western
Cannabinoid Receptor Agonists--pharmacology
Cytokines--biosynthesis
Hyperalgesia--chemically induced
Immunohistochemistry
Indoles--administration & dosage
Injections, Spinal
Macrophage Activation--drug effects
Male
Neuroglia--drug effects
Pain, Postoperative--chemically induced
Phosphorylation
Piperidines--antagonists & inhibitors
Posterior Horn Cells--drug effects
Rats
Rats, Sprague-Dawley
Receptor, Cannabinoid, CB2--biosynthesis
Receptors, N-Methyl-D-Aspartate--biosynthesis
Remifentanil
Spinal Cord--cytology