TY  - GEN
AU  - Offer,Steven M
AU  - Fossum,Croix C
AU  - Wegner,Natalie J
AU  - Stuflesser,Alexander J
AU  - Butterfield,Gabriel L
AU  - Diasio,Robert B
TI  - Comparative functional analysis of DPYD variants of potential clinical relevance to dihydropyrimidine dehydrogenase activity
SN  - 1538-7445
PY  - 2014///0706
KW  - Amino Acid Sequence
KW  - Antimetabolites, Antineoplastic
KW  - chemistry
KW  - Biotransformation
KW  - Dihydrouracil Dehydrogenase (NADP)
KW  - biosynthesis
KW  - Enzyme Assays
KW  - Fluorouracil
KW  - Gene Frequency
KW  - Genetic Association Studies
KW  - HEK293 Cells
KW  - Humans
KW  - Molecular Sequence Data
KW  - Mutation, Missense
N1  - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1158/0008-5472.CAN-13-2482
ER  -