TY - GEN AU - Savage,Kienan I AU - Matchett,Kyle B AU - Barros,Eliana M AU - Cooper,Kevin M AU - Irwin,Gareth W AU - Gorski,Julia J AU - Orr,Katy S AU - Vohhodina,Jekaterina AU - Kavanagh,Joy N AU - Madden,Angelina F AU - Powell,Alexander AU - Manti,Lorenzo AU - McDade,Simon S AU - Park,Ben Ho AU - Prise,Kevin M AU - McIntosh,Stuart A AU - Salto-Tellez,Manuel AU - Richard,Derek J AU - Elliott,Christopher T AU - Harkin,D Paul TI - BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability SN - 1538-7445 PY - 2014///0807 KW - BRCA1 Protein KW - deficiency KW - Breast KW - drug effects KW - Breast Neoplasms KW - chemically induced KW - Cytochrome P-450 CYP1A1 KW - genetics KW - DNA Breaks, Double-Stranded KW - DNA Repair KW - Estradiol KW - analogs & derivatives KW - Estrogens KW - metabolism KW - Estrogens, Catechol KW - pharmacology KW - Female KW - Genomic Instability KW - Humans KW - MCF-7 Cells N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-13-2611 ER -