TY - GEN AU - Campbell,Veronica T AU - Nadesan,Puviindran AU - Ali,S Amanda AU - Wang,Chang Ye Yale AU - Whetstone,Heather AU - Poon,Raymond AU - Wei,Qingxia AU - Keilty,John AU - Proctor,Jennifer AU - Wang,Lauren W AU - Apte,Suneel S AU - McGovern,Karen AU - Alman,Benjamin A AU - Wunder,Jay S TI - Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth SN - 1538-8514 PY - 2015///0102 KW - ADAMTS Proteins KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Calcinosis KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - Chondrosarcoma KW - genetics KW - Disease Models, Animal KW - Extracellular Matrix Proteins KW - Hedgehog Proteins KW - metabolism KW - Humans KW - Mice KW - Receptors, G-Protein-Coupled KW - antagonists & inhibitors KW - Signal Transduction KW - drug effects KW - Smoothened Receptor KW - Tumor Burden KW - Veratrum Alkaloids KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1535-7163.MCT-13-0731 ER -