Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner. [electronic resource]
- Clinical cancer research : an official journal of the American Association for Cancer Research May 2014
- 2727-39 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1557-3265
10.1158/1078-0432.CCR-13-2588 doi
Animals Antineoplastic Agents, Alkylating--pharmacology Brain Neoplasms--metabolism Breast Neoplasms--drug therapy Cell Line, Tumor DNA Modification Methylases--genetics DNA Repair Enzymes--genetics Dacarbazine--analogs & derivatives Dose-Response Relationship, Drug Drug Administration Schedule Female Humans Immunohistochemistry Kaplan-Meier Estimate MCF-7 Cells Mice Mice, Nude RNA Interference Temozolomide Treatment Outcome Triple Negative Breast Neoplasms--drug therapy Tumor Suppressor Proteins--genetics Xenograft Model Antitumor Assays