TY - GEN AU - Spencer,Andrew G AU - Labonte,Eric D AU - Rosenbaum,David P AU - Plato,Craig F AU - Carreras,Christopher W AU - Leadbetter,Michael R AU - Kozuka,Kenji AU - Kohler,Jill AU - Koo-McCoy,Samantha AU - He,Limin AU - Bell,Noah AU - Tabora,Jocelyn AU - Joly,Kristin M AU - Navre,Marc AU - Jacobs,Jeffrey W AU - Charmot,Dominique TI - Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans SN - 1946-6242 PY - 2014///1105 KW - Albuminuria KW - complications KW - Angiotensin-Converting Enzyme Inhibitors KW - pharmacology KW - Animals KW - Blood Pressure KW - drug effects KW - Disease Models, Animal KW - Dogs KW - Dose-Response Relationship, Drug KW - Electrolytes KW - urine KW - Enalapril KW - Feces KW - Healthy Volunteers KW - Humans KW - Hypertrophy KW - Intestinal Mucosa KW - metabolism KW - Intestines KW - Isoquinolines KW - administration & dosage KW - Kidney KW - Male KW - Myocardium KW - Nephrectomy KW - Rats KW - Rats, Sprague-Dawley KW - Renal Insufficiency, Chronic KW - Sodium KW - Sodium Chloride, Dietary KW - Sodium-Hydrogen Exchanger 3 KW - Sodium-Hydrogen Exchangers KW - antagonists & inhibitors KW - Sulfonamides N1 - Publication Type: Journal Article; Randomized Controlled Trial UR - https://doi.org/10.1126/scitranslmed.3007790 ER -