TY - GEN AU - Cheng,Chunwei AU - Liu,Yan AU - Balasis,Maria E AU - Simmons,Nicholas L AU - Li,Jerry AU - Song,Hao AU - Pan,Lili AU - Qin,Yong AU - Nicolaou,K C AU - Sebti,Said M AU - Li,Rongshi TI - Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim SN - 1660-3397 PY - 2014///1112 KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - chemistry KW - Bcl-2-Like Protein 11 KW - Blotting, Western KW - Breast Neoplasms KW - drug therapy KW - Catalysis KW - Cell Line, Tumor KW - Drug Screening Assays, Antitumor KW - Enzyme-Linked Immunosorbent Assay KW - Female KW - Humans KW - Indicators and Reagents KW - Isomerism KW - Magnetic Resonance Spectroscopy KW - Marine Toxins KW - pharmacology KW - Membrane Proteins KW - Myeloid Cell Leukemia Sequence 1 Protein KW - metabolism KW - Protein Binding KW - Proto-Oncogene Proteins KW - Pyrroles KW - chemical synthesis KW - Spectrophotometry, Ultraviolet KW - Structure-Activity Relationship KW - bcl-X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.3390/md12031335 ER -