TY - GEN AU - Komar-Stossel,Chani AU - Gross,Eitan AU - Dery,Elia AU - Corchia,Nathalie AU - Meir,Karen AU - Fried,Iris AU - Abramovitch,Rinat TI - TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI SN - 1932-6203 PY - 2015///0207 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Cell Proliferation KW - Cimetidine KW - administration & dosage KW - Cyclophosphamide KW - Deoxycytidine KW - Diclofenac KW - Drug Administration Schedule KW - Drug Combinations KW - Drug Synergism KW - Gene Amplification KW - Humans KW - Immunohistochemistry KW - Magnetic Resonance Imaging KW - methods KW - Male KW - Mice, Inbred NOD KW - Mice, SCID KW - N-Myc Proto-Oncogene Protein KW - Neovascularization, Pathologic KW - drug therapy KW - Neuroblastoma KW - blood supply KW - Nuclear Proteins KW - genetics KW - Oncogene Proteins KW - Platelet Endothelial Cell Adhesion Molecule-1 KW - metabolism KW - Sulfasalazine KW - Treatment Outcome KW - Tretinoin KW - Tumor Burden KW - Xenograft Model Antitumor Assays KW - Gemcitabine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0090224 ER -