Liang, Rong

Increased 14-3-3ΞΆ expression in the multidrug-resistant leukemia cell line HL-60/VCR as compared to the parental line mediates cell growth and apoptosis in part through modification of gene expression. [electronic resource] - Acta haematologica 2014 - 177-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1421-9662

10.1159/000357377 doi


14-3-3 Proteins--antagonists & inhibitors
ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1--biosynthesis
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Cell Cycle--drug effects
Drug Resistance, Multiple--genetics
Drug Resistance, Neoplasm--genetics
Gene Expression Profiling
Gene Expression Regulation, Leukemic
HL-60 Cells--drug effects
Humans
Myeloid Cell Leukemia Sequence 1 Protein--biosynthesis
Neoplasm Proteins--antagonists & inhibitors
Oligonucleotide Array Sequence Analysis
Proto-Oncogene Proteins c-bcl-2--biosynthesis
RNA Interference
RNA, Messenger--biosynthesis
RNA, Neoplasm--biosynthesis
RNA, Small Interfering--pharmacology
Subcellular Fractions--metabolism
Topoisomerase I Inhibitors--pharmacology
Topotecan--pharmacology
Vincristine--pharmacology