TY - GEN AU - Wishart,Thomas M AU - Mutsaers,Chantal A AU - Riessland,Markus AU - Reimer,Michell M AU - Hunter,Gillian AU - Hannam,Marie L AU - Eaton,Samantha L AU - Fuller,Heidi R AU - Roche,Sarah L AU - Somers,Eilidh AU - Morse,Robert AU - Young,Philip J AU - Lamont,Douglas J AU - Hammerschmidt,Matthias AU - Joshi,Anagha AU - Hohenstein,Peter AU - Morris,Glenn E AU - Parson,Simon H AU - Skehel,Paul A AU - Becker,Thomas AU - Robinson,Iain M AU - Becker,Catherina G AU - Wirth,Brunhilde AU - Gillingwater,Thomas H TI - Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy SN - 1558-8238 PY - 2014///0602 KW - Alternative Splicing KW - Animals KW - Disease Models, Animal KW - Drosophila KW - Homeostasis KW - Humans KW - Isoenzymes KW - genetics KW - Mice KW - Mice, Knockout KW - Mice, Mutant Strains KW - Mice, Transgenic KW - Muscle, Skeletal KW - metabolism KW - Muscular Atrophy, Spinal KW - etiology KW - RNA, Messenger KW - Rats KW - Signal Transduction KW - Spinal Cord KW - Survival of Motor Neuron 1 Protein KW - Ubiquitin KW - Ubiquitin-Activating Enzymes KW - antagonists & inhibitors KW - Zebrafish KW - beta Catenin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI71318 ER -